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Bioscience公司。这笔交易的总金额高达13.65亿美元,其中包括1.2亿美元的首付款和近期里程碑(7000万美元不可退还、不可抵扣的首付款,及后续5000万美元的近期开发里程碑款项)。在医药BD交易的潜规则里,首付款才是真正有含金量的部分。对于一款刚刚处于临床一期的早期资产而言,能够拿到7000万美元的首付款和5000万美元的近期里程碑,这种“重首付”足以证明这款产品的价格。金赛药业终于

Prometheus Biosciences,后被默沙东以百亿美元收购。他们重金买断GenSci098的海外权益,将其作为Yarrow公司的核心资产来打造,这种“押注式”的投入本身就是最高级别的背书。在RTW的估值模型中,GenSci098显然已经具备了颠覆现有治疗格局的潜力,改变了针对甲状腺眼病治疗机制。目前的市场霸主是安进旗下的Tepezza,这款年销数十亿美元的药物虽然开启了靶向治疗时代,却

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